Stem Cell Biophysics

Biophysics is an interdisciplinary science that applies the approaches & methods of physics to study biological structures. Biophysics covers all aspects of biological organization, from molecular to organismic and populations which includes structure & dynamics of molecules, cells & tissues, the influence of environment, energy transformation &  transfer, thermodynamics, biological motility, population dynamics & cell differentiation modeling, biomechanics & tissue rheology, non-linear phenomena, mathematical cybernetics modeling of complex systems, computational biology. The concept that the behavior of a stem cell can be modulated by factors in its immediate vicinity arose several decades ago in studies of spleen colony-forming cells, which were later appreciated to be the hematopoietic stem and progenitor cells.