Stem Cell apoptosis and signal transduction
Self-resumption and proliferation of stem cell populations is controlled by induction of apoptosis. Apoptosis is regulated by some of the same signal transduction pathways. Cell cycle control and apoptosis regulation closely link to cellular prolife ration, differentiation, senescence and cell death. Apoptosis is regulated by some of the signal transduction pathways by induction of apoptosis, self-renewal and proliferation of stem cell population. Apoptosis is also an important focus for stem cell transplantation, cell signaling, replacement therapy and tissue aging etc. stem cells will require full elucidation of the signal transduction cascades for proliferation, differentiation, and apoptosis.