Reprogramming Stem Cells: Computational Biology

Computational biology, a branch of biology involving the application of  computer science to the understanding and modeling of the structures and processes of biology,that referred to as bioinformatics. It entails the use of computational methods  for the representation and . apply advanced analysis techniques that make it possible to dissect complex collections of data from a wide range of technologies and sources.

The fields of stem cell biology and regenerative medicine research are fundamentally about understanding dynamic cellular processes such as development, reprogramming, repair, differentiation and the loss, acquisition or maintenance of pluripotency. Whereas bioinformatics is used to interpret the information produced by such technologies. pluripotency. In order to precisely decipher these processes at a molecular level, it is critical to identify and study key regulatory genes and transcriptional circuits. Modern high-throughput molecular profiling technologies provide a powerful approach to addressing these questions as they allow the profiling of tens of thousands of gene products in a single experiment. Whereas bioinformatics is used to interpret the information produced by such technologies.